12 research outputs found
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Public Engagement Technology for Bioacoustic Citizen Science
Inexpensive mobile devices offer new capabilities for non-specialist use in the field for the purpose of conservation. This thesis explores the potential for such devices to be used by citizen scientists interacting with bioacoustic data such as birdsong. This thesis describes design research and field evaluation, in collaboration with conservationists and educators, and technological artefacts implemented as mobile applications for interactive educational gaming and creative composition.
This thesis considers, from a participant-centric collaborative design approach, conservationists' demand for interactive artefacts to motivate engagement in citizen science through gameful and playful interactions. Drawing on theories of motivation, frequently applied to the study of Human-Computer Interaction (HCI), and on approaches to designing for motivational engagement, this thesis introduces a novel pair of frameworks for the analysis of technological artefacts and for assessing participant engagement with bioacoustic citizen science from both game interaction design and citizen science project participation perspectives. This thesis reviews current theories of playful and gameful interaction developed for collaborative learning, data analysis, and ground-truth development, describes a process for design and analysis of motivational mobile games and toys, and explores the affordances of various game elements and mechanics for engaging participation in bioacoustic citizen science.
This thesis proposes research into progressions for scaffolding engagement with citizen science projects where participants interact with data collection and analysis artefacts. The research process includes the development of multiple designs, analyses of which explore the efficacy of game interactions to motivate engagement through interaction progressions, given proposed analysis frameworks. This thesis presents analysed results of experiments examining the usability of, and data-quality from, several prototypes and software artefacts, in both laboratory conditions and the field. This thesis culminates with an assessment of the efficacy of proposed design analysis frameworks, an analysis of designed artefacts, and a discussion of how these designs increase intrinsic and extrinsic motivation for participant engagement and affect resultant bioacoustic citizen science data quantity and quality.Non
IMPLEMENTASI KEBIJAKAN PEMILIHAN KEPALA DAERAH (PEMILUKADA) DI KABUPATEN WAROPEN TAHUN 2020
The election of regional heads is a tool to increase public participation in the life of the nation and state and can be regulated through a mechanism of openness and equality for every citizen and is a process of transitioning leaders of a region that involves the real role of the public or the people in a sovereign manner. The objectives of this study: 1. To examine and analyze how the implementation of the Regional Head Election Policy (Pemilukada) in Waropen 2020. 2. To examine and analyze the supporting and inhibiting factors of the Implementation of the Regional Head Election Policy (Pemilukada) in Waropen 2020. The methodology of this research is descriptive qualitative. . The results of this study indicate that the Waropen Regional Head Election was carried out in the following indicators: 1). Standard policy targets. 2). Policy resources. 3). Communication between organizations. 4). Characteristics of the implementing agency. 5). Executor attitude. 6). Social, political and economic conditions. Of these six indicators, the independence and individual organizers of the event are still involved in supporting one of the candidates for the 2020 Regent and Deputy Regent. Conclusion. 1. Standards and policy objectives the statutory provisions in guarding the Regional Head Election are free, general, honest, fair and dignified as regulated in the regulations, but in practice there is a delay in entering the Covid-19 pandemic. 2. Policy resources and implementing characteristics are available both through regulations, but the consistency of the organizers is still questionable. 3. Filling in the composition of people or members of the organizers (KPUD commissioners, PPK/PPD, KPPS and KPU witnesses) is delayed. 4. Late budgeting affects the activities of each stage of the General Election. 5. Logistics and other supporting facilities were delayed. Suggestions: 1. It is hoped that the standards and policy objectives as regulated in the provisions of the legislation related to the Election of Regional Heads are supported by good quality organizers (KPUD, PPK/PPD, PPS and KPPS). 2. It is expected that the provision of policy resources and characteristics of implementers is on time on the indicators. a. Provision of various regulatory policies. b. Office and work administration. c. Fill in the composition of people or members of the organizers (KPUD commissioners, PPK/PPD, KPPS and KPU witnesses). d. Budgeting and e. Logistics and other supporting facilities. 3. It is expected that the attitude of implementers and communication between organizations related to the implementation of the Warope Regional Head Election remains independent or professional and is not involved in the succession of regional heads. 4. It is hoped that the quality of social democracy, health protocols, political maturity and the candidates for the Regent and Deputy Regent do not stipulate the Regional Revenue and Expenditure Budget (APBD)
Seri pengenalan tokoh: sekitar Proklamasi Kemerdekaan
Buku ini berjudul Seri Pengenalan Tokoh Sejarah. Fokus penulisan adalah tokoh-tokoh yang mempu nyai peranan pada saat Proklamasi Kemerdekaan Indonesia tanggal 17 Agustus 1945
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Effects of a mutation in the HSPE1 gene encoding the mitochondrial co-chaperonin HSP10 and its potential association with a neurological and developmental disorder
We here report molecular investigations of a missense mutation in the HSPE1 gene encoding the HSP10 subunit of the HSP60/ HSP10 chaperonin complex that assists protein folding in the mitochondrial matrix. The mutation was identified in an infant who came to clinical attention due to infantile spasms at three months of age. Clinical exome sequencing revealed heterozygosity for a HSPE1 NM_002157.2:c.217C>T de novo mutation causing replacement of leucine with phenylalanine at position 73 of the HSP10 protein. This variation has never been observed in public exome sequencing databases or the literature.To evaluate whether the mutation may be disease-associated we investigated its effects by in vitro and ex vivo studies. Our in vitro studies indicated that the purified mutant protein was functional, yet its thermal stability, spontaneous refolding propensity, and resistance to proteolytic treatment were profoundly impaired. Mass spectrometric analysis of patient fibroblasts revealed barely detectable levels of HSP10-p.Leu73Phe protein resulting in an almost 2-fold decrease of the ratio of HSP10 to HSP60 subunits. Amounts of the mitochondrial superoxide dismutase SOD2, a protein whose folding is known to strongly depend on the HSP60/HSP10 complex, were decreased to approximately 20% in patient fibroblasts in spite of unchanged SOD2 transcript levels. As a likely consequence, mitochondrial superoxide levels were increased about 2-fold. Although we cannot exclude other causative or contributing factors, our experimental data support the notion that the HSP10-p.Leu73Phe mutation could be the cause or a strong contributing factor for the disorder in the described patient
‘King Bottomless Empty Purse’ : Taxes, Avarice and Pastoral Care in the Swedish Reign of Christian I (1457–64)
Taxes were at the heart of late medieval political discourse because tax extraction was a tangible and sore point of interaction between subjects and their rulers. At no point in Swedish history was this more obvious than in the reign of Christian I (1457–64), and this article takes his reign as a moment to explore the parameters of the fiscal discourse where taxes were refuted or accepted. The first part examines the fiscal norms of law and custom, which were expressed in the pamphlets and chronicles that testify to Sweden’s burgeoning public sphere. The second part, however, focuses on the moralizing tenor of these narratives, where the tax abuse by Christian and other rulers is considered not only a crime but also a sin, and in particular avarice. The third part of the inquiry maps this moralizing tenor to its source in the penitential literature that guided the pastoral care of rulers and subjects alike. Taxes, this article contends, were not only talked about in the idioms of law and custom but also in the language of moral theology and pastoral care. Penance and politics were entwined in a way that shaped how taxes were talked about in public life.